What information does it provide?

The PrenatalSAFE® 3 test detects the aneuploidy of chromosomes 21, 18, 13 (Trisomy 21 - Down Syndrome, Trisomy 18 - Edwards Syndrome, Trisomy 13 - Patau Syndrome) and includes the determination of fetal sex (optional).  

The PrenatalSAFE® 5 test detects the aneuploidy of chromosomes 21, 18, 13 and sex chromosomes (Monosomy X - Turner Syndrome, XXX - Trisomy X, XXY - Klinefelter Syndrome, XYY - Jacobs Syndrome), and includes the determination of fetal sex (optional). 

In addition to the aneuploidy of chromosomes 21, 18, 13 and of the sex chromosomes (X and Y), the Prenatal SAFE® Plus test also detects chromosomal trisomy 9 and 16 (optional) as well as sub-microscopic structures, such as some common microdeletion syndromes.

With PrenatalSAFE® Karyo test, a non-invasive RhSafe® test is offered complimentary to determine fetal Rh(D) status in Rh(D) negative mother and an Rh(D) positive male partner. 


The PrenatalSAFE® KARYO test allows detecting aneuploidy on all chromosomes with results similar to an invasive analysis of the karyotype. 

PrenatalSAFE® Complete identifies the findings of PrenatalSAFE® Karyo and mutations responsible for serious genetic diseases (5 hereditary and 44 recessive de novo). 

PrenatalSAFE® Complete Plus allows identification of the findings of PrenatalSAFE® Complete and the 9 most common microdeletion syndromes.