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PrenatalSAFE® is a non-invasive prenatal test which, by analysing the free circulating fetal DNA isolated from a sample of maternal blood, provides 6 levels of information in Pregnancy. The test allows for the detection of aneuploidies and microdeletion syndromes, from the most common to the rarest, structural alterations in all the chromosomes of the fetus and the presence of mutations related to serious genetic diseases.

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Who should Take PrenatalSAFE® test

The PrenatalSAFE® test is the best test in the following cases: 
  • Pregnancies where invasive prenatal diagnosis is contraindicated (eg risk of spontaneous abortion) 
  • Positive first trimester (Bi-Test) 
  • Advanced maternal age (> 35 years ) 
  • Advanced paternal age (> 40 years) 
  • Positivity to the first or second trimester screening tests 
  • Ultrasound picture of fetal abnormalities suggestive of aneuploidy 
  • Personal / family history of chromosomal abnormalities
  • Partner(s) of the carrier pair (i) of Balanced translocation. 
  • Couples with advanced paternal age (PrenatalSafe Complete)

All pregnant women with a gestational age of at least 10 weeks can get the test.

 

PrenatalSAFE® test is suitable for: 

• Single pregnancies
- obtained through natural conception 
- obtained with homologous assisted fertilization techniques 
- obtained with heterologous assisted fertilization techniques 
• Twin pregnancies
- obtained through natural conception 
- obtained with fertilization techniques assisted homologues 
- obtained with heterologous assisted fertilization techniques 
• Previous pregnancies completed
• Previous pregnancies hesitated in spontaneous abortion or followed by voluntary interruption of pregnancy 

For technical reasons, the determination of sex chromosomes is not offered for twin pregnancies.